Cased | An international multicenter study led by Vincenzo Russotto, from the School of Medicine and Surgery of the University of Milano-Bicocca (Italy), reveals that 45.2 percent of patients undergoing this procedure experienced at least one major clinical event, and one in three (32.8 percent) died in the ICU: Among the clinical events, the main one was cardiovascular instability, present in 42, 6 percent of patientss. The next most common was severe hypoxemia (9.3 percent) and then cardiac arrest (3.1 percent). | +INFORMATION
We are aware that sedation and indiscriminate intubation have been carried out on patients who presented respiratory failure after the administration of these toxic substances.</p >
The neurologists and neuroscientists at Massachusetts General Hospital in a specific study on the effects of this prolonged sedation on the neurological function of patients concluded that some sedatives, such as PROPOFOL, can prolong anesthesia and help patients not wake up.
Another recent study published in the New England Journal of Medicine de Shibani Mukerji, MD, PhD, associate director of the Neuro-Infectious Diseases Unit of Mass General, shows that the post-mortem brains of ventilated patients with COVID-19 have a lesion hypoxic.
The essay ‘International Study to Understand the Impact and Best Practices of Airway Management in Critically Ill Patients’ (‘Intube’) , which included the participation of 2,964 patients from 29 countries, which shows its statistical strength, carried out before the pandemic (between October 2018 and July 2019) but with conclusions that can be applied to patients intubated by Covid, reveals that 45.2 per One hundred percent of patients undergoing tracheal intubation experience at least one major clinical event, and one in three (32.8 percent) die in the ICU.
*To these protocols that have killed hundreds of thousands of people we must add two factors keys: The total withdrawal of food after admission to the ICU and isolation and solitary confinement, aggravating and tortuous events for patients.
An international multicenter study led by Vincenzo Russotto, from the School of Medicine and Surgery of the University of Milano-Bicocca (Italy), reveals that < strong>45.2 percent of patients undergoing this procedure experienced at least one major clinical event, and one in three (32 .8 percent) died in the ICU:
Among the clinical events, the main one was cardiovascular instability, present in 42.6 per cent of patients. The next most common was severe hypoxemia (9.3 percent), followed by cardiac arrest (3.1 percent).
The study on adverse events after tracheal intubation has been published in JAMA and concludes that “cardiopulmonary events they happened frequently.”
The essay ‘International Study to Understand the Impact and Best Practices of Airway Management in Critically Ill Patients’ (‘Intube’) was conducted before the pandemic (between October 2018 and July 2019), but its conclusions can be applied to patients intubated by Covid.
In addition, it had the participation of 2,964 patients from 29 countries, which shows its statistical strength.
Original source: https:/ /www.elhospital.com/temas/Riesgos-y-complicaciones-de-la-ventilacion-mecanica+8054960
We leave a fragment extracted from elhospital .com regarding RISKS AND COMPLICATIONS OF MECHANICAL VENTILATION, where it indicates thatventilator-induced lung injury represents a significant percentage of respiratory complications in ICU patients:
Mechanical ventilation inevitably subjects the lung to potential physical damage, known as “induced lung injury”. ventilator” (IVPI), which represents a significant percentage of respiratory complications in patients in intensive care units.
Two factors have been proposed as contributing to its development. The first is physical damage due to overdistention, mainly seen in lungs with heterogeneous lesions, where healthy areas are prone to greater inflation when applying positive pressure ventilation. This type of damage is characterized by significant tissue inflammation, edema, formation of hyaline membranes, and release of inflammatory mediators into the circulation. The second proposed factor is the repeated opening and closing of atelectatic alveoli in the injured lung.
In addition to damage at the tissue level (alveolar), mechanical ventilation has also been associated with induced diaphragmatic dysfunction in the first 24 to 48 hours,< strong> by suppression of the normal spontaneous activity of the respiratory muscles, which alters blood flow and resting time of the muscle, and causes important cellular changes, such as atrophy, myofibrillar loss, proteolysis, vacuole formation, and alteration in the mitochondria (…)